Best Polynucleotide (PN) Injections in Dubai 2025 – Reviews, Results & Prices
- EDEN AESTHETICS Clinic
- 4 hours ago
- 11 min read
Dubai’s glow-up era is still in full swing—and polynucleotide injections (often called PN injections or “salmon DNA skin boosters”) are the treatment everyone is asking about in 2025. From crepey under-eyes to fine lines, post-sun stress, and loss of bounce, PN therapy is designed to repair and rejuvenate skin—not just plump it temporarily. In this deep dive, we explain the science in simple language, compare leading brands, share guidance on prices in Dubai, and answer the most common questions patients ask at EDEN AESTHETICS Clinic.
What are Polynucleotide (PN) Injections?
Polynucleotides are purified DNA fragments (frequently sourced from salmon or made bio-identical), used as a biostimulator that encourages your skin to repair, rebuild, and rehydrate from within. Instead of simply “filling” space like classic hyaluronic acid (HA) fillers, PN acts more like a signal and scaffold: it helps soothe inflammation, supports fibroblast activity, improves extracellular matrix quality, and enhances microcirculation. The result? Progressive gains in texture, elasticity, luminosity, and resilience—especially valuable in a hot, sunny climate like Dubai, where photoaging is accelerated.
PN vs. traditional HA boosters: HA skinboosters are phenomenal hydrators; PN goes beyond hydration to target cellular repair and tissue homeostasis. Many patients in Dubai choose a combination plan—for example, PN to repair and HA skinboosters to amplify radiance.
Who is a Good Candidate in Dubai?
You may benefit from polynucleotide skin rejuvenation if you notice:
Fine lines, crepey under-eyes, or overall dullness
Textural roughness after acne or sun exposure
Thinner, drier skin with reduced bounce
Early laxity on the neck or hands
Skin tones: PN is suitable across Fitzpatrick I–VI; in Dubai, we commonly treat Fitzpatrick III–V and pay particular attention to heat, pigment safety, and sunscreen habits.
Who should avoid PN? We’ll assess this at consultation, but we typically postpone in pregnancy/breastfeeding, active infections, autoimmune flares, or known fish/salmon allergies (depending on the product). Always disclose medical history and medications to your clinician.
Treatment Areas & Protocols (Face, Under-Eyes, Neck, Hands)
Under-eyes: One of Dubai’s most requested indications. PN helps crepey texture, fine lines, and fatigue-related dullness by improving dermal quality.
Full face: Global skin quality (clarity, softness, elasticity).
Neck & décolletage: Crepiness and photoaging patches.
Hands: Skin thinning and visible texture.
Typical plan: an initial series of 2–4 sessions spaced 2–4 weeks apart, followed by maintenance every 4–6 months. Protocols vary with brand, skin baseline, and whether PN is combined with HA boosters, PRP, exosomes, microneedling RF, or lasers.
Best Polynucleotide (PN) Injections Brands in Dubai (2025): PLURYAL, Chroma & More
PLURYAL: A modern PN-based biostimulation range focused on skin quality restoration—supporting hydration balance, elasticity, and dermal repair. Clinics often choose lighter formulations for delicate areas like the under-eyes and medium-density options for broader face/neck rejuvenation. Protocols are typically course-based (2–4 sessions) with tailored maintenance.
Chroma: Chroma’s polynucleotide solutions emphasize long-chain biostimulation to improve texture, luminosity, and resilience. With variants suitable for periorbital (under-eye) and full-face indications—as well as neck, décolletage, and hands—Chroma PN can act as a foundation therapy before HA skinboosters, microneedling RF, or laser treatments.
Nucleofill & others: A newer generation of PN biostimulators offering different concentrations and rheology, enabling clinicians to fine-tune placement for fragile versus thicker skin zones and to combine intelligently with complementary treatments for amplified outcomes.
How we choose at EDEN AESTHETICS: We match brand/viscosity and injection technique to your anatomy, lifestyle, and goals. Under-eye protocols, for example, may favor finer textures and cannula-based approaches for precision and comfort.
PN vs PRP vs Profhilo vs HA Skinboosters vs Exosomes
Patients often ask how PN compares to other beloved treatments in Dubai. Here’s a practical, patient-friendly summary.
At-a-Glance Comparison
Treatment | Mechanism | Best For | Typical Sessions | Downtime | Onset | Longevity | Typical Dubai Price Band* | Notes |
PN (Polynucleotides) | Bio-repair, anti-inflammatory, ECM support | Texture, under-eyes, elasticity | 2–4 | Mild (1–3 days) | Progressive (2–6 wks) | 4–8+ months | AED 1,000–2,500 / session | Combines well with HA boosters |
PRP | Autologous growth factors | Overall glow, hair, scars (varies) | 3–4 | Mild | Gradual (weeks) | 6–12 months | AED 800–1,800 / session | Natural, result varies by biology |
Profhilo | HA hybrid for deep hydration & remodeling | Hydration, firmness | 2 sessions (4 wks) | Minimal | Quick glow (1–2 wks) | 6–9 months | AED 1,200–1,900 / session | Often paired with PN |
HA Skinboosters | HA dermal hydration | Radiance, fine lines | 2–3 | Minimal | Fast | 6–9 months | AED 900–1,600 / session | Great pre-events |
Exosomes | Cell-signal vesicles | Redness, recovery, texture | Protocol-dependent | Minimal | Progressive | Variable | AED 1,200–2,500 / session | Usually add-on to devices |
*Prices are indicative ranges across Dubai in 2025; see detailed pricing below. Exact quotes provided after consultation at EDEN AESTHETICS Clinic.
Takeaway: For repair-led rejuvenation—especially delicate areas like under-eyes—PN is a strong core choice. Hydration-focused goals may favor Profhilo/HA boosters, while PRP and exosomes can be supportive in bespoke plans. Many of our best outcomes at EDEN AESTHETICS come from thoughtful combinations staged over several weeks.
Under-Eye PN Injections in Dubai: What to Expect
The under-eye region is thin and vulnerable to crepiness and fine lines. PN addresses skin quality, not volume: it’s ideal when you want fresher, tighter-looking under-eyes without an obviously “filled” look.
Technique: micro-aliquots or blunt cannula for even, gentle placement.
Comfort: topical numbing; most patients describe minimal discomfort.
Downtime: slight puffiness or tiny dots for 1–3 days; concealer can usually be worn the next day.
Results: gradual clarity and smoothness over 2–6 weeks, with further improvements as your tissue remodels.
If hollows/tear troughs are primarily volume-deficient, your clinician may suggest HA filler in addition—or a staged plan (PN first to improve tissue quality, then cautious filler if needed).
Results Timeline, Downtime & Longevity
Same day: mild swelling; a subtle “fresh” look for some.
2–6 weeks: visible gains in texture, bounce, and clarity.
Durability: often 4–8+ months depending on area, lifestyle, and adjunct treatments.
Downtime: typically 1–3 days of mild swelling/bruising; strict SPF is non-negotiable under the Dubai sun.
Pro tip for Dubai skin: Pair PN with a dermatologist-guided regimen (vitamin C AM, retinoid PM if appropriate, and a high-protection broad-spectrum SPF) for amplified and longer-lasting radiance.
Reviews & Patient Experiences (2025)
Themes we consistently hear from PN patients at EDEN AESTHETICS:
“My skin quality just looks better—more refined and elastic.”
“The under-eye crepiness is much improved; makeup sits better.”
“It’s natural-looking—friends say I look rested, not ‘done’.”
For PLURYAL injections Dubai reviews, patients often mention comfort and steady improvements after the second session. Chroma fans highlight texture and bounce, especially on the cheeks and under-eyes after a structured course.
We never publish patient photos or quotes without explicit consent. Ask us in-clinic to view verified before/after portfolios and talk through which protocol is best for you.
2025 Price Guide: PN Injection Cost in Dubai
We know you’re comparing Polynucleotide treatment cost in Dubai and searching for the best PN therapy Dubai price. Final pricing depends on your treatment plan, brand, areas, and whether you bundle with HA boosters, PRP, exosomes, or devices.
Indicative Dubai price ranges (2025):
Under-eyes (single session): AED 900–1,500
Full face (single session): AED 1,200–2,500
Neck or hands (single session): AED 1,000–1,800
Course packages (3 sessions): AED 3,000–6,000 depending on brand/areas
Chroma PN Dubai cost (per session): AED 1,200–2,200
Pluryal PN (per session): AED 1,000–1,800
We’ll provide an exact, personalized quote after your medical consultation at EDEN AESTHETICS Clinic.
Value tips:
Book course packages for efficiency and savings.
Consider combination plans (e.g., PN + Profhilo) for amplified results.
Ask about seasonal offers or installment options.
Safety, Side Effects & Aftercare
Common and temporary:
mild swelling, tiny injection marks, light bruising, transient tenderness.
Less common:
small lumps (usually settle), redness, sensitivity.
Rare:
hypersensitivity or infection—managed promptly under clinical protocols.
Aftercare in Dubai:
Avoid heat/sauna, strenuous exercise, or alcohol on the same day
No facials or aggressive skincare for 48–72 hours
SPF 50 daily; reapply if outdoors
Follow your personalized skincare plan and attend scheduled reviews
We operate under DHA-compliant standards with single-use sterile consumables and evidence-based protocols.
Why Choose EDEN AESTHETICS for Polynucleotide Injections in Dubai?
Doctor-led care with specific expertise in biostimulators and under-eye techniques
Access to leading PN brands (e.g., Pluryal, Chroma) matched to your skin and goals
Tailored combination strategies that respect downtime and event timelines
Business Bay location, discreet environment, multilingual team, and VIP options
Award-winning clinic ethos (Best Aesthetic Clinic recognition)
Ready to plan your glow strategy? Book a private consultation and let’s design a plan that fits your timeline and lifestyle.
A Typical Patient Journey at EDEN AESTHETICS
Consultation & skin imaging (history, goals, budget, timeline)
Protocol selection (brand, area, session count, combo options)
Informed consent and topical anesthesia
Precise injection (micro-aliquots or cannula)
Cool compress & aftercare guidance
Review at 2–6 weeks; plan maintenance or combinations for long-term glow
Before & After Gallery Guidance
We photograph your progress under consistent lighting and without filters. For course-based PN therapy, expect visible improvements from week 2 onward, with peak refinement typically around weeks 6–12 as dermal repair accumulates. Individual outcomes vary by baseline skin quality and adherence to aftercare; we set realistic, healthy expectations and review images at each follow-up.
PN Brands at a Glance (2025)
Brand | Origin | Feel/Viscosity | Main Uses | Typical Protocol | Notable Strengths |
PLURYAL | Luxembourg | Light-to-medium PN viscosities; eye-friendly options | Face, under-eyes, neck | 2–4 sessions, 2–4 weeks apart | Versatile portfolio for delicate zones; comfort-focused placement; steady gains in texture/elasticity |
Chroma | Austria | Multiple PN variants suited to indication | Face, under-eyes, scars | 3–4 sessions, ~3–4 weeks apart | Noticeable elasticity and “rested” look; adaptable across face, neck, décolletage, hands |
Nucleofill / other PN | EU/Korea | Range of viscosities | Face, neck, hands | Tailored to area/skin thickness | Flexible matching by area; easy to combine with HA boosters or device-based therapies |
FAQs: Polynucleotide Injections Dubai (2025)
1) What are polynucleotide (PN) injections and how do they work?
PN are purified DNA fragments that act as a biostimulator, encouraging tissue repair, hydration balance, and elasticity. They calm inflammation, support fibroblasts, and improve the skin’s extracellular matrix, leading to smoother, bouncier, more radiant skin over several weeks.
2) Are PN injections the same as a “Salmon DNA skin booster”?
Yes—many people use the term “Salmon DNA skin booster Dubai” to describe certain PN products (e.g., Rejuran Healer). Not all PN are salmon-derived, but the category is similar in repair-first intent.
3) What are the top PN injection benefits in Dubai’s climate?
Key PN injection benefits include improved texture, elasticity, fine-line softening, better makeup hold, and a more rested look—highly valuable for skin facing sun, heat, and AC exposure typical in Dubai.
4) Are polynucleotide injections safe for under-eyes?
When performed by trained clinicians, Polynucleotide injections under eyes are a popular, low-volume strategy to reduce crepiness and boost skin quality without “filler bulk.” Technique and product choice matter—under-eyes need finesse.
5) How many sessions do I need and how often?
Most plans include 2–4 sessions spaced 2–4 weeks apart, then maintenance every 4–6 months. Your exact plan depends on brand, area(s), baseline, and whether we combine PN with Profhilo/HA boosters/PRP/exosomes.
6) What is the polynucleotide treatment cost in Dubai (2025)?
Indicative ranges: AED 900–1,500 for under-eyes; AED 1,200–2,500 for full face; AED 1,000–1,800 for neck/hands; packages (3 sessions): AED 3,000–6,000. We’ll confirm your personalized quote at consultation.
7) What is the best PN therapy Dubai price—can I get packages?
The “best PN therapy Dubai price” balances brand quality, sterile protocols, and expert technique. Course packages typically offer better value and outcomes. Ask us about seasonal offers and installments.
8) PLURYAL injections Dubai reviews: what do patients say?
Patients commonly report steadier texture refinement, improved elasticity, and a natural, rested look—often becoming noticeable after the second session. Reviews frequently highlight under-eye improvements, smoother makeup application, and overall skin quality gains without a “filled” appearance.
9) Chroma PN Dubai cost: what should I expect?
Indicatively, Chroma PN sessions in Dubai range from AED 1,200–2,200 per session, depending on area treated and the number of vials used. Package pricing is available, and many treatment plans include 3–4 sessions spaced a few weeks apart for optimal, cumulative results.
10) PN vs hyaluronic acid skin boosters: which should I choose?
HA skinboosters excel at hydration and glow; PN focuses on repair and resilience. In practice, we often combine them: PN to restore, HA to super-hydrate—especially for event timelines.
11) PN vs PRP: which is better?
They’re different tools. PRP is your own plasma (biology-dependent), while PN offers standardized biostimulation. Many patients benefit from staged combinations—we’ll tailor based on goals and downtime.
12) Do PN injections help acne scars or pigmentation?
PN can improve texture and tone evenness by supporting tissue quality. For scars or pigment, we may pair PN with microneedling RF, lasers, or exosomes for a comprehensive plan.
13) Can PN replace filler under the eyes?
PN improves skin quality but does not “fill” hollows. If volume loss is the main issue, we may add precise HA filler—often after an initial PN course to strengthen the tissue.
14) What downtime should I expect?
Most patients experience 1–3 days of mild swelling or tiny dots. Bruising is possible but usually minor. You can typically resume desk work the next day.
15) How soon will I see results, and how long do they last?
Expect a progressive glow with texture and elasticity gains from 2–6 weeks onward. Results often last 4–8+ months, with maintenance every 4–6 months.
16) Are the results natural-looking?
Yes. PN prioritizes quality over volume, so results tend to look refreshed, not “overdone.” Friends usually notice you look rested.
17) Are biostimulator polynucleotides Dubai treatments suitable for all skin tones?
Yes, with appropriate technique and aftercare. We routinely treat a wide range of tones; SPF discipline is crucial in Dubai’s sun.
18) Is the treatment painful? Do you use numbing?
We apply topical anesthetic. Most patients describe PN injections as well-tolerated with minimal discomfort—especially when using cannula for delicate areas.
19) Any risks or side effects I should know?
Temporary swelling, redness, small bruises, or tenderness are common. Rare events (e.g., infection, hypersensitivity) are mitigated with sterile technique and medical oversight.
20) Can I combine PN with Profhilo, PRP, exosomes, or microneedling RF?
Absolutely. We design staged plans (e.g., PN first, then HA booster; or PN with Microneedling RF spaced a few weeks apart). Combining modalities often maximizes outcomes.
21) Is “Salmon DNA skin booster Dubai” only for the face?
No. While face and under-eyes are popular, we also treat neck, hands, and décolletage depending on skin needs and goals.
22) How do I book polynucleotide injections in Dubai at EDEN AESTHETICS?
Message us on WhatsApp or call the clinic. We’ll schedule your consultation, build your plan, and review transparent pricing—including packages.
Conclusion: Your Repair-First Glow Strategy for 2025
If your goal is skin that looks naturally refreshed—not overfilled—polynucleotide injections are one of the smartest choices in Dubai right now. By prioritizing cellular repair and resilience, PN therapy improves texture, elasticity, and that tricky under-eye crepiness, with results that build steadily over 2–6 weeks and maintain beautifully with periodic top-ups. Compared with hydration-led options (Profhilo/HA skinboosters) or biology-dependent treatments (PRP), PN sits at the center of a modern, combination plan—and it pairs especially well with HA boosters, microneedling RF, or exosomes for truly elevated outcomes.
At EDEN AESTHETICS Clinic in Business Bay, we offer leading formulations like Pluryal and Chroma and customize protocols to your skin, timeline, and comfort. Expect transparent guidance on polynucleotide treatment cost in Dubai, package recommendations for value, and meticulous technique—particularly for polynucleotide injections under eyes where finesse matters most.
Key takeaways for your decision:
· PN = repair-first biostimulation with natural-looking results.
· Excellent for under-eyes, face, neck, and hands; beautiful in combination plans.
· Prices vary by brand/area/course; packages often deliver the best PN therapy Dubai price.
· Sun-smart aftercare and consistent maintenance maximize longevity.
Ready to find out whether PN, a Salmon DNA skin booster, or a tailored combo is right for you? Book a private consultation at EDEN AESTHETICS and we’ll craft a plan—and a price—that fits your skin and your 2025 goals.
and get a Welcoming Voucher for
Your First Treatment Call us Now
EDEN AESTHETICS Clinic Dubai +971 4 577 4796